adipose tissue lipolysis physiology and nutrition

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Regulation of lipid metabolism in adipose tissue ...- adipose tissue lipolysis physiology and nutrition ,Feb 28, 2007·The increased mobilization of lipid fuel is brought about by the differential actions of various counter-regulatory hormones on adipose tissue blood flow and adipose tissue lipolysis through lipoprotein lipase and hormone-sensitive lipase, resulting in increased availability of non-esterified fatty acids as a source of fuel.Dissociation between adipose tissue fluxes ... - PhysiologyApr 01, 2007·Triglyceride (TG) synthesis and degradation (lipolysis) can also now be measured in adipose tissue by administration of 2 H 2 O (5, 39, 44). Measurement of TG synthesis contributes another metric of adipose tissue metabolism in vivo and also allows for more accurate assessment of DNL rates ( 39 ).



Metabolic and hemodynamic response of adipose tissue to ...

Metabolic and hemodynamic response of adipose tissue to angiotensin II. Boschmann M(1), Ringel J, Klaus S, Sharma AM. Author information: (1)Department of Biochemistry and Physiology of Nutrition, German Institute of Human Nutrition, Potsdam, Germany. [email protected]

Lipolysis and the integrated physiology of lipid energy ...

Nov 01, 2008·Lipolysis is best viewed in its physiological context, not as an isolated phenomenon. There are several lipolytic states. Prolonged fasting is characterized by an increased dependence on lipolysis for provision of fatty acids (FA) 3 as an energy source, and by low circulating levels of insulin and catecholamines. In contrast, the lipolysis of acute stress is intense, brief and triggered by ...

The physiology and pharmacology of adipose tissue ...

The regulation of adipose tissue lipolysis occupies a key position in the metabolic concert of carbohydrates and lipids, and insulin plays the role of the conductor. Insulin favours the storage of fat in adipose tissue by 3 mechanisms: — 1. it inhibits lipolysis; — 2. increases the glucose uptake, lipogenesis and reësterification of free fatty acids; — 3. enhances the activity of ...

Fuel selection in white adipose tissue | Proceedings of ...

Lafontan, M. & Langin, D. ( 1995 ). Cellular aspects of fuel mobilization and selection in white adipocytes. Proceedings of the Nutrition Society 54, 49 – 63. CrossRef Google Scholar PubMed. Leboeuf, B. ( 1965 ). Regulation of fatty acid esterification in adipose tissue incubated in vitro.

Adipose tissue hyaluronan production improves systemic ...

Aug 10, 2021·Cellular Has2 overexpression primes cells for lipolysis. Adipose tissue Has2 overexpression leads to a cellular ... Department of Nutrition and Integrative Physiology…

Concordance of in vivo microdialysis and in vitro ...

The in vivo studies, on the other hand, are supposed to give relevant data about tissue physiology interacting with other metabolic systems at the body level. OBJECTIVE: To investigate the concordance between the results on responsiveness to stimulation of lipolysis from in vivo microdialysis and in vitro isolated adipocytes.

Adipocyte pseudohypoxia suppresses lipolysis and ...

In this study, we demonstrate that adipose PHD2 inhibition plays a key role in the suppression of adipocyte lipolysis. Adipose Phd2 gene ablation in mice enhanced adiposity, with a parallel increase in adipose vascularization associated with reduced circulating nonesterified fatty acid levels and normal glucose homeostasis.

Diet‐induced changes in subcutaneous adipose tissue blood ...

Lene Simonsen, Lotte H. Enevoldsen, Bente Stallknecht, Jens Bülow, Effects of local α2‐adrenergic receptor blockade on adipose tissue lipolysis during prolonged systemic adrenaline infusion in normal man, Clinical Physiology and Functional Imaging, 10.1111/j.1475-097X.2007.00781.x, 28, 2, …

Obesity and the role of adipose tissue in inflammation and ...

Feb 01, 2006·In fact, adipose tissue macrophages are responsible for almost all adipose tissue TNF-α expression and significant amounts of IL-6 and inducible nitric oxide synthase expression . Of particular note, Xu et al ( 51 ) reported that the increased expression of inflammation-specific genes by macrophages in the adipose tissue of obese mice preceded ...

Physiology of Fat Loss - UNM

Physiology of Fat Loss. The Physiology of Fat Loss. Mike Deyhle, Christine Mermier, Ph.D. and Len Kravitz, Ph.D. Introduction. Fat serves many important functions in the human body. For example, fat provides a key role for the structure and flexibility of cell membranes and also helps to regulate substance movement through the cell membranes.

Nutritional and hormonal control of lipolysis ... - Physiology

In summary, lipolysis of adipocytes isolated from adipose tissue of seabream is clearly modulated by the nutritional condition of the fish. These cells increase the lipolytic activity in the presence of glucagon and GH. However, further studies are needed to understand fully the endocrine regulation of adipose tissue metabolism in fish.

Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient ...

Dec 12, 2017·Mechanistic studies suggest that adipose KLF15 regulates key genes of triglyceride synthesis and inhibits lipolytic action, thereby promoting lipid storage in an insulin-dependent manner. Finally, AK15KO mice demonstrate accelerated lipolysis and altered systemic energetics (e.g., locomotion, ketogenesis) during fasting conditions.

Adipose tissue: Adipogenesis and physiology (2nd part ...

Request PDF | Adipose tissue: Adipogenesis and physiology (2nd part) | The adipose tissue contains body fat stores which are modulated by the ability of adipocytes to differentiate and adaptation ...

Regulation of adipocyte lipolysis | Nutrition Research ...

May 28, 2014·Control of lipolysis. Lipolysis constitutes the catabolic process leading to the breakdown of TAG into glycerol and NEFA in the adipose tissue (Reference Arner 2).Basal lipolytic activity of adipocytes is conditioned by sex, age, physical activity, fat depot location, species and genetic variance, whereas stimulated adipocyte lipolysis is regulated by multiple factors, which are depicted in ...

Obesity and metabolic disease: is adipose tissue the ...

For instance, lipolysis is down regulated, the sensitivity of lipolysis to insulin is reduced and there are disturbances in the regulation of adipose tissue blood flow. However, when examined critically these changes canbe seen as adaptations to the increased adipose tissue mass, making the situation betterrather than worse.

Regulation of adipocyte lipolysis | Nutrition Research ...

May 28, 2014·Control of lipolysis. Lipolysis constitutes the catabolic process leading to the breakdown of TAG into glycerol and NEFA in the adipose tissue (Reference Arner …

Lipolysis: definition, pathway, regulation in adipose ...

Lipolysis: process, enzymes, products, regulation in adipose tissue. Lipolysis is defined as the biochemical pathway responsible for the hydrolysis of triacylglycerols (TAG) or triglycerides into non-esterified fatty acids (NEFA) and glycerol. The involved enzymes are called lipases.

Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient ...

Dec 12, 2017·Mechanistic studies suggest that adipose KLF15 regulates key genes of triglyceride synthesis and inhibits lipolytic action, thereby promoting lipid storage in an insulin-dependent manner. Finally, AK15KO mice demonstrate accelerated lipolysis and altered systemic energetics (e.g., locomotion, ketogenesis) during fasting conditions.

Adrenergic Regulation of Adipose Tissue Lipolysis in ...

Rates of lipolysis in adipose tissue increased in early lactation and were greater on the LE diet, while adipose tissue lipogenesis decreased (P < 0.05) in early lactation on LE but maintained on HE. Lipogenesis was maintained slightly higher in the dry period and first week of lactation in HG animals, but was lower at peak lactation, when HG ...

Physiological and metabolic differences between visceral ...

Nov 09, 2017·Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT) have different structures and metabolic functions and play different roles in the regulation of the mammal endocrine system. However, little is known about morphology and physiological and metabolic functions between VAT and SCAT in fish.

Adipose Tissue Lipolysis | SpringerLink

高达10%返现·Nov 28, 2012·Adipose tissue lipolysis is the process by which stored triacylglycerols in the lipid droplet of adipocytes are released as non-esterified fatty acids to be …

Nutritional and hormonal control of lipolysis ... - Physiology

In summary, lipolysis of adipocytes isolated from adipose tissue of seabream is clearly modulated by the nutritional condition of the fish. These cells increase the lipolytic activity in the presence of glucagon and GH. However, further studies are needed to understand fully the endocrine regulation of adipose tissue metabolism in fish.

Frontiers | In vitro Lipolysis and Leptin Production of ...

Dec 10, 2020·Adipose tissue plays key roles in energy homeostasis. Understanding its metabolism and regulation is essential to predict the impact of environmental changes on wildlife health, especially in fasting-adapted species. However, in vivo experimental work in wild vertebrates can be challenging. We have developed a novel in vitro approach of precision-cut adipose tissue slices from northern ...

Chronic stress and adipose tissue in the anorexic state ...

Aug 10, 2020·Fat mass and adipose tissue distribution. According to the Diagnostic and Statistical Manual of Mental Disorders, anorexia nervosa is defined as a restricted energy intake relative to the requirement due to the intense fear of weight gain even at a significantly low weight, where the body mass index (BMI) is below 18 in adults and the corresponding BMI percentile in children and …

Adrenergic Regulation of Adipose Tissue Lipolysis in ...

Rates of lipolysis in adipose tissue increased in early lactation and were greater on the LE diet, while adipose tissue lipogenesis decreased (P < 0.05) in early lactation on LE but maintained on HE. Lipogenesis was maintained slightly higher in the dry period and first week of lactation in HG animals, but was lower at peak lactation, when HG ...

Lipolysis and lipid mobilization in human adipose tissue ...

Sep 01, 2009·Adipose tissue (AT) is the body’s largest energy reservoir and a major source of metabolic fuel. Most energy reserves in the human body are stored in fat cells as triacylglycerols (TAGs). Factors that control the storage and mobilization of TAG in adipocytes are important regulators of fat accumulation in the various fat depots [1] .