biodegradable tissue matrix structure

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US5932539A - Biodegradable polymer matrix for tissue ...- biodegradable tissue matrix structure ,Novel biodegradable amphiphilic polymers are described. Preferred polymers have a lipophilic binding moiety coupled covalently to a hydrophilic tissue adhesion moiety through a divalent linker comprising a natural metabolite or a polymer biodegradable into a natural metabolite. In one embodiment the biodegradable polymers of the invention exhibit the property of self-assembly characteristic of ...Biodegradable hydrogel with nanogel cross-linked structure ...We previously reported that the nanogel of cholesterol-bearing pullulan (CHP) served as a promising carrier for proteins and hydrophobic drugs. In this study, we developed biodegradable hydrrogel with nanogel cross-linked structure (CHPA-PEOSH gel) for tissue engineering.



3D biodegradable scaffolds of polycaprolactone with ...

Jun 11, 2018·3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study

Biodegradable polymer Matrix Nanocomposites for Tissue ...

Dec 03, 2012·Biodegradable polymer Matrix Nanocomposites for Tissue Engineering 1. ... Cells are often implanted or seeded into an artificial structure capable of supporting …

Biodegradable polymer - Wikipedia

Biodegradable polymers are a special class of polymer that breaks down after its intended purpose by bacterial decomposition process to result in natural byproducts such as gases (CO 2, N 2), water, biomass, and inorganic salts. These polymers are found both naturally and synthetically made, and largely consist of ester, amide, and ether functional groups.

Biodegradable synthetic polymeric fibrous matrix ...

Apr 16, 1990·Methods and artificial matrices for the growth and implantation of cartilaginous structures and surfaces and bone are disclosed. In the preferred embodiments, chondrocytes are grown on biodegradable, biocompatible fibrous polymeric matrices. Optionally, the cells are proliferated in vitro until an adequate cell volume and density has developed for the cells to survive and proliferate in vivo.

Biodegradable polymer matrix nanocomposites for bone ...

Jan 01, 2019·In recent years, a variety of nanocomposites made of biodegradable polymers are being explored and exploited for the use in tissue engineering applications [17]. Even, these biodegradable polymer matrix nanocomposites have been found effective for tissue generation in the field of bone tissue engineering [18].

Recent Progress on Biodegradable Tissue Engineering ...

Mar 28, 2021·3D biodegradable polymer scaffolds with a porous structure usually act as temporary template for seeding, adhesion, growth and proliferation of living cells to guide regeneration and formation of new tissues, while the biodegradable polymer matrix is subjected to biodegradation [5,6].

Experience with NovoSorb® Biodegradable Temporising Matrix ...

Jun 03, 2021·The NovoSorb® Biodegradable Temporising Matrix (BTM) (PolyNovo Biomaterials Pty Ltd., Port Melbourne, VIC, Australia) is a fully synthetic dermal matrix that can be used to reconstruct complex wounds. It consists of a 2-mm thick NovoSorb biodegradable polyurethane open cell foam covered by a non-biodegradable sealing membrane.

(PDF) Poly(ε-caprolactone) grafted dextran biodegradable ...

Poly(e-caprolactone) Grafted Dextran Biodegradable Electrospun Matrix: A Novel Scaffold for Tissue Engineering Madhab Prasad Bajgai,1 Santosh Aryal,2 Shanta Raj Bhattarai,1 K. C. Remant Bahadur,3 Kawn-Woo Kim,1 Hak Yong Kim4 1 Department of Bionanosystem Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea 2 Center for Healthcare Technology Development, …

Tissue engineering - Wikipedia

Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. Tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose ...

Decellularized sciatic nerve matrix as a biodegradable ...

Recently, the use of conduits in nerve injury repair, made possible by tissue engineering, has shown therapeutic potential. We manufactured a biodegradable, collagen-based nerve conduit containing decellularized sciatic nerve matrix and compared this with a silicone conduit for peripheral nerve regeneration using a rat model.

Biodegradable materials for bone defect repair | Military ...

Nov 10, 2020·Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers. In the treatment of bone defects, scaffolds made of biodegradable materials can provide a crawling bridge for new bone tissue in the gap and a platform for cells and growth factors to …

Biodegradable Polymers - ScienceDirect

Jan 01, 2014·Elucidation of the biodegradation mechanism and its dependence on the polyurethane structure and composition have led to the development of biodegradable polyurethanes for a variety of tissue-engineering applications such as meniscal reconstruction , myocardial repair and vascular tissues . Design of biodegradable polyurethanes has required ...

Anisotropic Porous Biodegradable Scaffolds for ...

Tissues that are formed into these scaffolds are initially formed in the isotropic porous structure and since most tissues have significant anisotropic extracellular matrix components and concomitant mechanical properties, the formed tissues have no structural and functional relationships with the native tissues.

Biodegradable synthetic polymeric fibrous matrix ...

The matrices are formed of a biodegradable, non-degradable, or combination of biodegradable and non-degradable materials which have been configured to produce high cell densities by allowing adequate diffusion of nutrients and waste as well as gas exchange, while in vitro or in vivo, prior to remodeling and integration with host tissue.

(PDF) Biodegradable Polymer Scaffold for Tissue Engineering

Biodegradable Polymer Scaffold for Tissue Engineering 29 100. M.S. Cortizo, S.M. Molinuevo, A.M and Cortizo, Biocompatibility and biodegradation of polyester and polyfumarate

Recent trends in the application of widely used natural ...

The goal of a biomaterial is to support the bone tissue regeneration process at the defect site and eventually degrade in situ and get replaced with the newly generated bone tissue. Nanocomposite biomaterials are a relatively new class of materials that incorporate a biopolymeric and biodegradable matrix structure with bioactive and easily ...

Biodegradable hydrogel with nanogel cross-linked structure ...

We previously reported that the nanogel of cholesterol-bearing pullulan (CHP) served as a promising carrier for proteins and hydrophobic drugs. In this study, we developed biodegradable hydrrogel with nanogel cross-linked structure (CHPA-PEOSH gel) for tissue engineering.

Anisotropic Porous Biodegradable Scaffolds for ...

Tissues that are formed into these scaffolds are initially formed in the isotropic porous structure and since most tissues have significant anisotropic extracellular matrix components and concomitant mechanical properties, the formed tissues have no structural and functional relationships with the native tissues.

Product - ologen™ Collagen Matrix

About ologen™ Collagen Matrix. ologen™ Collagen Matrix is a biodegradable and implantable ECM mimic specifically configured to support and modulate tissue repair processes in connective and epithelial ocular tissues. As a soft and pliable medical device, ologen™ Collagen Matrix is highly absorbent and serves as a dynamic physiological ...

Biodegradable polymer matrix nanocomposites for tissue ...

Nov 01, 2010·Therefore, the incorporation of hydroxyapatite in a polymeric matrix has to overcome processing and dispersion challenges, since it is of great interest to the …

(PDF) Fibrin: A Natural Biodegradable Scaffold in Vascular ...

2 Cells Tissues Organs 084 Shaikh /Callaghan /Kavanagh /Burke / Grace /McGloughlin CTO084.indd 2 29.04.2008 15:36:25 Most synthetic polymer scaffolds used in vascular tissue the matrix degradation time and the reconstruction of a engineering are biodegradable, one of the most desirable new matrix [Cebotari et al., 2002].

Biodegradable collagen matrix (Ologen™) implant and ...

Oct 24, 2015·Scleromalacia, in the form of scleral thinning, melting, and necrosis, is a potentially serious complication of pterygium excision. This study introduces a new biodegradable material, Ologen™ collagen matrix (OCM), to repair scleral thinning as an alternative to preserved scleral tissue, and evaluates the long-term outcomes of OCM for ocular surface reconstruction surgery.

Biodegradable polymer matrix nanocomposites for tissue ...

Request PDF | Biodegradable polymer matrix nanocomposites for tissue engineering: A review | Nanocomposites have emerged in the last two decades as an efficient strategy to upgrade the structural ...

Novel biodegradable electrospun membrane: scaffold for ...

The objective of this study was fabrication of nanofibrous matrix from novel biodegradable poly(p-dioxanone-co-L-lactide)-block-poly(ethylene glycol) …

Biodegradable scaffolds for tissue engineering - ScienceDirect

Jan 01, 2009·In many cases, the matrices and scaffolds would ideally be made of biodegradable polymers whose properties closely resemble those of the extracellular matrix (ECM), a soft, tough and elastomeric proteinaceous network that provides mechanical stability and structural integrity to tissues and organs. 56 Within the natural biomaterials available ...

Decellularized sciatic nerve matrix as a biodegradable ...

Recently, the use of conduits in nerve injury repair, made possible by tissue engineering, has shown therapeutic potential. We manufactured a biodegradable, collagen-based nerve conduit containing decellularized sciatic nerve matrix and compared this with a silicone conduit for peripheral nerve regeneration using a rat model.